|
KMID : 1234920170170010037
|
|
Journal of Korean Oriental Association for Study of Obesity
2017 Volume.17 No. 1 p.37 ~ p.45
|
|
|
Anti-Obesity Effect of Panax Ginseng in Animal Models: Study Protocol for a Systematic Review and Meta-Analysis
|
|
Cho Jae-Heung
Kim Koh-Woon
Park Hye-Sung
Yoon Ye-Ji
Song Mi-Yeon
|
|
|
Abstract
|
|
|
|
Recently the global epidemic problem of obesity has stimulated intense interest in the study of physiological mechanisms using animal models as a way to gain crucial data required for translation to human studies. Panax ginseng has been reported to have anti-obesity or anti- diabetic effects in many animal studies; however, there have been few studies investigating human obesity. Herein, we will assess and examine the evidence supporting the anti-obesity effect of Panax ginseng in animal models with respect to anthropometric and metabolic outcomes. We will include controlled, comparative studies assessing the effect of Panax ginseng in preclinical studies of obesity. Panax ginseng will be administered during or following the induction of experimental obesity. The primary outcome measure will be anthropometric assessment and the secondary outcome measures will include adipose tissue weight, total amount of food consumed and metabolic parameters. We will search MEDLINE, Embase, PubMed, Web of Science, and Scopus without language, publication date, or other restrictions. Ethical approval will not be necessary as the data collected in this study will not be individual patient data, consequently there will be no concerns about violations of privacy. After finishing the whole procedure, the results will be disseminated by publication in a peer-reviewed journal or presented at a relevant conference. This protocol has been registered on the Collaborative Approach to Meta-Analysis and Review of Animal Data from Experimental Studies (CAMARADES) website (http://www.camarades.info).
|
|
|
KEYWORD
|
|
|
Obesity, Panax, Animal experimentation, Study protocol, Systematic review
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|
|